Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin

Tuberous sclerosis complex (TSC) is an autosomal dominant disease caused by mutations in either the TSC1 (encodes hamartin) or TSC2 (encodes tuberin) genes. Patients with TSC have hamartomas in various organs throughout the whole body, most notably in the brain, skin, eye, heart, kidney and lung. To...

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Detalles Bibliográficos
Autores principales: Kim, Seok-Hyung, Speirs, Christina K., Solnica-Krezel, Lilianna, Ess, Kevin C.
Formato: Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046101/
https://www.ncbi.nlm.nih.gov/pubmed/20959633
http://dx.doi.org/10.1242/dmm.005587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046101/
https://www.ncbi.nlm.nih.gov/pubmed/20959633
http://dx.doi.org/10.1242/dmm.005587

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