Quantitative Proteomics Identifies the Myb-Binding Protein p160 as a Novel Target of the von Hippel-Lindau Tumor Suppressor

BACKGROUND: The von Hippel-Lindau (VHL) tumor suppressor gene encodes a component of a ubiquitin ligase complex, which is best understood as a negative regulator of hypoxia inducible factor (HIF). VHL ubiquitinates and degrades the α subunits of HIF, and this is proposed to suppress tumorigenesis an...

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Detalles Bibliográficos
Autores principales: Lai, Yanlai, Qiao, Mei, Song, Meihua, Weintraub, Susan T., Shiio, Yuzuru
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046137/
https://www.ncbi.nlm.nih.gov/pubmed/21386990
http://dx.doi.org/10.1371/journal.pone.0016975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046137/
https://www.ncbi.nlm.nih.gov/pubmed/21386990
http://dx.doi.org/10.1371/journal.pone.0016975

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