PKCα and PKCδ Regulate ADAM17-Mediated Ectodomain Shedding of Heparin Binding-EGF through Separate Pathways

Epidermal growth factor receptor (EGFR) signalling is initiated by the release of EGFR-ligands from membrane-anchored precursors, a process termed ectodomain shedding. This proteolytic event, mainly executed by A Disintegrin And Metalloproteases (ADAMs), is regulated by a number of signal transducti...

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Detalles Bibliográficos
Autores principales: Kveiborg, Marie, Instrell, Rachael, Rowlands, Christina, Howell, Michael, Parker, Peter J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046143/
https://www.ncbi.nlm.nih.gov/pubmed/21386996
http://dx.doi.org/10.1371/journal.pone.0017168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046143/
https://www.ncbi.nlm.nih.gov/pubmed/21386996
http://dx.doi.org/10.1371/journal.pone.0017168

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