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Mechanical Influences on Morphogenesis of the Knee Joint Revealed through Morphological, Molecular and Computational Analysis of Immobilised Embryos

Very little is known about the regulation of morphogenesis in synovial joints. Mechanical forces generated from muscle contractions are required for normal development of several aspects of normal skeletogenesis. Here we show that biophysical stimuli generated by muscle contractions impact multiple...

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Detalles Bibliográficos
Autores principales: Roddy, Karen A., Prendergast, Patrick J., Murphy, Paula
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046254/
https://www.ncbi.nlm.nih.gov/pubmed/21386908
http://dx.doi.org/10.1371/journal.pone.0017526