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Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells

INTRODUCTION: The human epidermal growth factor receptor 2 (HER2) is a validated therapeutic target in breast cancer. Heterodimerization of HER2 with other HER family members results in enhanced tyrosine phosphorylation and activation of signal transduction pathways. HER2 overexpression increases th...

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Detalles Bibliográficos
Autores principales:	Jin, Quanri, Yuan, Linda X, Boulbes, Delphine, Baek, Jong Min, Wang, Ying Nai, Gomez-Cabello, Daniel, Hawke, David H, Yeung, Sai Ching, Lee, Mong Hong, Hortobagyi, Gabriel N, Hung, Mien Chie, Esteva, Francisco J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046439/ https://www.ncbi.nlm.nih.gov/pubmed/21080941 http://dx.doi.org/10.1186/bcr2777

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