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Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors
INTRODUCTION: The actin binding protein Mammalian enabled (Mena), has been implicated in the metastatic progression of solid tumors in humans. Mena expression level in primary tumors is correlated with metastasis in breast, cervical, colorectal and pancreatic cancers. Cells expressing high Mena leve...
Autores principales: | Roussos, Evanthia T, Wang, Yarong, Wyckoff, Jeffrey B, Sellers, Rani S, Wang, Weigang, Li, Jiufeng, Pollard, Jeffrey W, Gertler, Frank B, Condeelis, John S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046446/ https://www.ncbi.nlm.nih.gov/pubmed/21108830 http://dx.doi.org/10.1186/bcr2784 |
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