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A GA microsatellite in the Fli1 promoter modulates gene expression and is associated with systemic lupus erythematosus patients without nephritis
INTRODUCTION: The transcription factor Fli1 is implicated in the pathogenesis of systemic lupus erythematosus (SLE). Recently, a GA(n )polymorphic microsatellite was characterized in the mouse Fli1 promoter that modulates promoter activity and is truncated in two lupus mouse models compared to non-a...
Autores principales: | Morris, Erin E, Amria, May Y, Kistner-Griffin, Emily, Svenson, John L, Kamen, Diane L, Gilkeson, Gary S, Nowling, Tamara K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046520/ https://www.ncbi.nlm.nih.gov/pubmed/21087477 http://dx.doi.org/10.1186/ar3189 |
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