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Surprising negative association between IgG1 allotype disparity and anti-adalimumab formation: a cohort study

INTRODUCTION: The human monoclonal antibody adalimumab is known to induce an anti-globulin response in some adalimumab-treated patients. Antibodies against adalimumab (AAA) are associated with non-response to treatment. Immunoglobulins, such as adalimumab, carry allotypes which represent slight diff...

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Detalles Bibliográficos
Autores principales:	Bartelds, Geertje M, de Groot, Els, Nurmohamed, Michael T, Hart, Margreet HL, van Eede, Peter H, Wijbrandts, Carla A, Crusius, Jakob BA, Dijkmans, Ben AC, Tak, Paul Peter, Aarden, Lucien, Wolbink, Gerrit J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046534/ https://www.ncbi.nlm.nih.gov/pubmed/21187010 http://dx.doi.org/10.1186/ar3208

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