Cargando…

Tests for Genetic Interactions in Type 1 Diabetes: Linkage and Stratification Analyses of 4,422 Affected Sib-Pairs

OBJECTIVE: Interactions between genetic and environmental factors lead to immune dysregulation causing type 1 diabetes and other autoimmune disorders. Recently, many common genetic variants have been associated with type 1 diabetes risk, but each has modest individual effects. Familial clustering of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morahan, Grant, Mehta, Munish, James, Ian, Chen, Wei-Min, Akolkar, Beena, Erlich, Henry A., Hilner, Joan E., Julier, Cécile, Nerup, Jørn, Nierras, Concepcion, Pociot, Flemming, Todd, John A., Rich, Stephen S.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046821/ https://www.ncbi.nlm.nih.gov/pubmed/21266329 http://dx.doi.org/10.2337/db10-1195

Ejemplares similares

Genome-Wide Scan for Linkage to Type 1 Diabetes in 2,496 Multiplex Families From the Type 1 Diabetes Genetics Consortium
por: Concannon, Patrick, et al.
Publicado: (2009)

Genetics of Type 1 Diabetes: What's Next?
por: Pociot, Flemming, et al.
Publicado: (2010)

A Human Type 1 Diabetes Susceptibility Locus Maps to Chromosome 21q22.3
por: Concannon, Patrick, et al.
Publicado: (2008)

Genome-wide association study and meta-analysis finds over 40 loci affect risk of type 1 diabetes
por: Barrett, Jeffrey C., et al.
Publicado: (2009)

Evidence of Gene-Gene Interaction and Age-at-Diagnosis Effects in Type 1 Diabetes
por: Howson, Joanna M.M., et al.
Publicado: (2012)

Design and Measurement of Nonislet-Specific Autoantibodies for the Type 1 Diabetes Genetics Consortium Autoantibody Workshop
por: Akolkar, Beena, et al.
Publicado: (2015)

Confirmation of novel type 1 diabetes risk loci in families
por: Cooper, J. D., et al.
Publicado: (2012)

Designing and implementing sample and data collection for an international genetics study: the Type 1 Diabetes Genetics Consortium (T1DGC)
por: Hilner, Joan E, et al.
Publicado: (2010)

Proteome Analysis—A Novel Approach to Understand the Pathogenesis of Type 1 Diabetes Mellitus
por: Karlsen, Allan E., et al.
Publicado: (2001)

Measurement of islet cell antibodies in the Type 1 Diabetes Genetics Consortium: efforts to harmonize procedures among the laboratories
por: Bingley, Polly J, et al.
Publicado: (2010)

Estimation of Recombination Rate and Maternal Linkage Disequilibrium in Half-Sibs
por: Hampel, Alexander, et al.
Publicado: (2018)

Incorporating quantitative variables into linkage analysis using affected sib pairs
por: Chiu, Yen-Feng, et al.
Publicado: (2007)

Joint modeling of linkage and association using affected sib-pair data
por: Chen, Ming-Huei, et al.
Publicado: (2007)

A statistical method for adjusting covariates in linkage analysis with sib pairs
por: Wu, Colin O, et al.
Publicado: (2003)

Theoretical aspects of applying sib-pair linkage tests to livestock species
por: Götz, KU, et al.
Publicado: (1992)

Collection and processing of whole blood for transformation of peripheral blood mononuclear cells and extraction of DNA: the Type 1 Diabetes Genetics Consortium
por: Rosinger, Silke, et al.
Publicado: (2010)

Design considerations in a sib-pair study of linkage for susceptibility loci in cancer
por: Kerber, Richard A, et al.
Publicado: (2008)

Assessing genotype × environment interaction in linkage mapping using affected sib pairs
por: Chen, Yi-Shin, et al.
Publicado: (2007)

Linkage analysis of alcohol dependence using both affected and discordant sib pairs
por: Shih, Pei-Ying, et al.
Publicado: (2005)

Danish children born with glutamic acid decarboxylase-65 and islet antigen-2 autoantibodies at birth had an increased risk to develop type 1 diabetes
por: Eising, Stefanie, et al.
Publicado: (2011)

Importance sampling method of correction for multiple testing in affected sib-pair linkage analysis
por: Klein, Alison P, et al.
Publicado: (2003)

Genome-wide linkage analysis of inguinal hernia in pigs using affected sib pairs
por: Grindflek, Eli, et al.
Publicado: (2006)

A genome-wide search for linkage to allergic rhinitis in Danish sib-pair families
por: Kruse, Lisbeth Venø, et al.
Publicado: (2012)

Inclusion of unaffected sibs increases power in model-free linkage analysis of a behavioral trait
por: Plancoulaine, Sabine, et al.
Publicado: (2005)

Multivariate sib-pair linkage analysis of longitudinal phenotypes by three step-wise analysis approaches
por: Guo, Zheng, et al.
Publicado: (2003)

Use of sib-pair linkage methods for the estimation of the genetic variance at a quantitative trait locus
por: Hamann, H, et al.
Publicado: (1995)

No evidence of linkage to chromosome 1q42.2–43 in 131 prostate cancer families from the ACTANE Consortium
por: Singh, R
Publicado: (2000)

Linkage analysis between dominant and co-dominant makers in full-sib families of out-breeding species
por: Alves, Alexandre Alonso, et al.
Publicado: (2010)

Integrative analysis for finding genes and networks involved in diabetes and other complex diseases
por: Bergholdt, Regine, et al.
Publicado: (2007)

Sib1, Sib2, and Sib3 proteins are required for ferrichrome-mediated cross-feeding interaction between Schizosaccharomyces pombe and Saccharomyces cerevisiae
por: Brault, Ariane, et al.
Publicado: (2022)

Review on 422 Cataracts Done by "Smith's Method"
por: Trivedi, Ram Nath
Publicado: (1913)

Biobanking, consent, and commercialization in international genetics research: the Type 1 Diabetes Genetics Consortium
por: Hall, Mark A, et al.
Publicado: (2010)

Mysterious SiB(3): Identifying the Relation between α- and β-SiB(3)
por: Eklöf, Daniel, et al.
Publicado: (2019)

Children at onset of type 1 diabetes show altered N-glycosylation of plasma proteins and IgG
por: Rudman, Najda, et al.
Publicado: (2022)

PM422. Creatine Phospho Kinase Elevations with Clozapine
por: Takahashi, Yuka
Publicado: (2016)

THU422 Laboratory Evaluation For Etiologies Of Secondary Osteoporosis
por: Shah, Nandi, et al.
Publicado: (2023)

A multilocus likelihood approach to joint modeling of linkage, parental diplotype and gene order in a full-sib family
por: Lu, Qing, et al.
Publicado: (2004)

A nonparametric regression-based linkage scan of rheumatoid factor-IgM using sib-pair squared sums and differences
por: Ghosh, Saurabh, et al.
Publicado: (2007)

Genomic prediction in hybrid breeding: II. Reciprocal recurrent genomic selection with full-sib and half-sib families
por: Melchinger, Albrecht E., et al.
Publicado: (2023)

42.2 INFLAMMATION AND GUT MICROBIOME IN FIRST-EPISODE PSYCHOSIS
por: Suvisaari, Jaana, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_4suc6oo28q5mj1s6c9thkt5f6e