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Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes

OBJECTIVE: Genetic defects in human pericentrin (PCNT), encoding the centrosomal protein pericentrin, cause a form of osteodysplastic primordial dwarfism that is sometimes reported to be associated with diabetes. We thus set out to determine the prevalence of diabetes and insulin resistance among pa...

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Detalles Bibliográficos
Autores principales:	Huang-Doran, Isabel, Bicknell, Louise S., Finucane, Francis M., Rocha, Nuno, Porter, Keith M., Tung, Y.C. Loraine, Szekeres, Ferenc, Krook, Anna, Nolan, John J., O’Driscoll, Mark, Bober, Michael, O’Rahilly, Stephen, Jackson, Andrew P., Semple, Robert K.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Pathophysiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046854/ https://www.ncbi.nlm.nih.gov/pubmed/21270239 http://dx.doi.org/10.2337/db10-1334

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