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Activation of Peroxisome Proliferator–Activated Receptor δ Inhibits Streptozotocin-Induced Diabetic Nephropathy Through Anti-Inflammatory Mechanisms in Mice
OBJECTIVE: Activation of the nuclear hormone receptor peroxisome proliferator–activated receptor (PPAR)-δ has been shown to improve insulin resistance, adiposity, and plasma HDL levels. Several studies have reported that activation of PPARδ is atheroprotective; however, the role of PPARδ in renal fu...
Autores principales: | Matsushita, Yuichi, Ogawa, Daisuke, Wada, Jun, Yamamoto, Noriko, Shikata, Kenichi, Sato, Chikage, Tachibana, Hiromi, Toyota, Noriko, Makino, Hirofumi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046857/ https://www.ncbi.nlm.nih.gov/pubmed/21270242 http://dx.doi.org/10.2337/db10-1361 |
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