Efficacy of CMX001 as a Post Exposure Antiviral in New Zealand White Rabbits Infected with Rabbitpox Virus, a Model for Orthopoxvirus Infections of Humans

CMX001, a lipophilic nucleotide analog formed by covalently linking 3-(hexdecyloxy)propan-1-ol to cidofovir (CDV), is being developed as a treatment for smallpox. In the absence of human cases of smallpox, new treatments must be tested for efficacy in animal models. Previously, we demonstrated the e...

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Detalles Bibliográficos
Autores principales: Rice, Amanda D., Adams, Mathew M., Wallace, Greg, Burrage, Andrew M., Lindsey, Scott F., Smith, Andrew J., Swetnam, Daniele, Manning, Brandi R., Gray, Stacey A., Lampert, Bernhard, Foster, Scott, Lanier, Randall, Robertson, Alice, Painter, George, Moyer, Richard W.
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046869/
https://www.ncbi.nlm.nih.gov/pubmed/21373379
http://dx.doi.org/10.3390/v3010047

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