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BALB/c Mice Infected with Antimony Treatment Refractory Isolate of Leishmania braziliensis Present Severe Lesions due to IL-4 Production

BACKGROUND: Leishmania braziliensis is the main causative agent of cutaneous leishmaniasis in Brazil. Protection against infection is related to development of Th1 responses, but the mechanisms that mediate susceptibility are still poorly understood. Murine models have been the most important tools...

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Detalles Bibliográficos
Autores principales: Costa, Diego L., Carregaro, Vanessa, Lima-Júnior, Djalma S., Silva, Neide M., Milanezi, Cristiane M., Cardoso, Cristina R., Giudice, Ângela, de Jesus, Amélia R., Carvalho, Edgar M., Almeida, Roque P., Silva, João S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046967/
https://www.ncbi.nlm.nih.gov/pubmed/21390155
http://dx.doi.org/10.1371/journal.pntd.0000965