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Efficient Feeder-Free Episomal Reprogramming with Small Molecules

Genetic reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs) could offer replenishable cell sources for transplantation therapies. To fulfill their promises, human iPSCs will ideally be free of exogenous DNA (footprint-free), and be derived and cultured in chemically define...

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Detalles Bibliográficos
Autores principales: Yu, Junying, Chau, Kevin Fongching, Vodyanik, Maxim A., Jiang, Jinlan, Jiang, Yong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046978/
https://www.ncbi.nlm.nih.gov/pubmed/21390254
http://dx.doi.org/10.1371/journal.pone.0017557