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HIF-1α antagonizes p53-mediated apoptosis by triggering HIPK2 degradation
Many human diseases are characterized by the development of tissue hypoxia. Hypoxia-inducible factor (HIF) is a transcription factor that regulates fundamental cellular processes in response to changes in oxygen concentration, such as angiogenesis, survival, and alterations in metabolism. The levels...
Autores principales: | Nardinocchi, Lavinia, Puca, Rosa, D'Orazi, Gabriella |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047137/ https://www.ncbi.nlm.nih.gov/pubmed/21248371 |
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