Cargando…

A reflection-based localized surface plasmon resonance fiber-optic probe for biochemical sensing

We report the fabrication and characterization of an optical fiber biochemical sensing probe based on localized surface plasmon resonance (LSPR) and spectra reflection. Ordered array of gold nanodots was fabricated on the optical fiber end facet using electron-beam lithography (EBL). We experimental...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Yongbin, Zou, Yang, Lindquist, Robert G.
Formato: Texto
Lenguaje:English
Publicado: Optical Society of America 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047353/
https://www.ncbi.nlm.nih.gov/pubmed/21412453
http://dx.doi.org/10.1364/BOE.2.000478
_version_ 1782199029983084544
author Lin, Yongbin
Zou, Yang
Lindquist, Robert G.
author_facet Lin, Yongbin
Zou, Yang
Lindquist, Robert G.
author_sort Lin, Yongbin
collection PubMed
description We report the fabrication and characterization of an optical fiber biochemical sensing probe based on localized surface plasmon resonance (LSPR) and spectra reflection. Ordered array of gold nanodots was fabricated on the optical fiber end facet using electron-beam lithography (EBL). We experimentally demonstrated for the first time the blue shift of the LSPR scattering spectrum with respected to the LSPR extinction spectrum, which had been predicted theoretically. High sensitivity [195.72 nm/refractive index unit (RIU)] of this sensor for detecting changes in the bulk refractive indices has been demonstrated. The label-free affinity bio-molecules sensing capability has also been demonstrated using biotin and streptavidin as the receptor and the analyte.
format Text
id pubmed-3047353
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Optical Society of America
record_format MEDLINE/PubMed
spelling pubmed-30473532011-03-16 A reflection-based localized surface plasmon resonance fiber-optic probe for biochemical sensing Lin, Yongbin Zou, Yang Lindquist, Robert G. Biomed Opt Express Biosensors and Molecular Diagnostics We report the fabrication and characterization of an optical fiber biochemical sensing probe based on localized surface plasmon resonance (LSPR) and spectra reflection. Ordered array of gold nanodots was fabricated on the optical fiber end facet using electron-beam lithography (EBL). We experimentally demonstrated for the first time the blue shift of the LSPR scattering spectrum with respected to the LSPR extinction spectrum, which had been predicted theoretically. High sensitivity [195.72 nm/refractive index unit (RIU)] of this sensor for detecting changes in the bulk refractive indices has been demonstrated. The label-free affinity bio-molecules sensing capability has also been demonstrated using biotin and streptavidin as the receptor and the analyte. Optical Society of America 2011-02-01 /pmc/articles/PMC3047353/ /pubmed/21412453 http://dx.doi.org/10.1364/BOE.2.000478 Text en ©2011 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Biosensors and Molecular Diagnostics
Lin, Yongbin
Zou, Yang
Lindquist, Robert G.
A reflection-based localized surface plasmon resonance fiber-optic probe for biochemical sensing
title A reflection-based localized surface plasmon resonance fiber-optic probe for biochemical sensing
title_full A reflection-based localized surface plasmon resonance fiber-optic probe for biochemical sensing
title_fullStr A reflection-based localized surface plasmon resonance fiber-optic probe for biochemical sensing
title_full_unstemmed A reflection-based localized surface plasmon resonance fiber-optic probe for biochemical sensing
title_short A reflection-based localized surface plasmon resonance fiber-optic probe for biochemical sensing
title_sort reflection-based localized surface plasmon resonance fiber-optic probe for biochemical sensing
topic Biosensors and Molecular Diagnostics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047353/
https://www.ncbi.nlm.nih.gov/pubmed/21412453
http://dx.doi.org/10.1364/BOE.2.000478
work_keys_str_mv AT linyongbin areflectionbasedlocalizedsurfaceplasmonresonancefiberopticprobeforbiochemicalsensing
AT zouyang areflectionbasedlocalizedsurfaceplasmonresonancefiberopticprobeforbiochemicalsensing
AT lindquistrobertg areflectionbasedlocalizedsurfaceplasmonresonancefiberopticprobeforbiochemicalsensing
AT linyongbin reflectionbasedlocalizedsurfaceplasmonresonancefiberopticprobeforbiochemicalsensing
AT zouyang reflectionbasedlocalizedsurfaceplasmonresonancefiberopticprobeforbiochemicalsensing
AT lindquistrobertg reflectionbasedlocalizedsurfaceplasmonresonancefiberopticprobeforbiochemicalsensing