Synthesis of some nucleosides derivatives from L- rhamnose with expected biological activity

Practical procedures for production of variously blocked compounds from L-rhamnose have been developed. These compounds are highly useful as indirect β-L-rhamnosyl donors. This approach represents a new method for the synthesis of aromatic nucleoside analogues and the synthesis of (3S, 4S, 5S, 6R) 3...

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Detalles Bibliográficos
Autor principal: Ghoneim, Amira Atef
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047426/
https://www.ncbi.nlm.nih.gov/pubmed/21314940
http://dx.doi.org/10.1186/1752-153X-5-7
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author Ghoneim, Amira Atef
author_facet Ghoneim, Amira Atef
author_sort Ghoneim, Amira Atef
collection PubMed
description Practical procedures for production of variously blocked compounds from L-rhamnose have been developed. These compounds are highly useful as indirect β-L-rhamnosyl donors. This approach represents a new method for the synthesis of aromatic nucleoside analogues and the synthesis of (3S, 4S, 5S, 6R) 3, 4, 5-triacetoxy-2-methyl-7,9-diaza-1-oxa-spiro [4,5]decane-10-one-8-thione (7).
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spelling pubmed-30474262011-03-03 Synthesis of some nucleosides derivatives from L- rhamnose with expected biological activity Ghoneim, Amira Atef Chem Cent J Research Article Practical procedures for production of variously blocked compounds from L-rhamnose have been developed. These compounds are highly useful as indirect β-L-rhamnosyl donors. This approach represents a new method for the synthesis of aromatic nucleoside analogues and the synthesis of (3S, 4S, 5S, 6R) 3, 4, 5-triacetoxy-2-methyl-7,9-diaza-1-oxa-spiro [4,5]decane-10-one-8-thione (7). BioMed Central 2011-02-11 /pmc/articles/PMC3047426/ /pubmed/21314940 http://dx.doi.org/10.1186/1752-153X-5-7 Text en Copyright ©2011 Ghoneim et al
spellingShingle Research Article
Ghoneim, Amira Atef
Synthesis of some nucleosides derivatives from L- rhamnose with expected biological activity
title Synthesis of some nucleosides derivatives from L- rhamnose with expected biological activity
title_full Synthesis of some nucleosides derivatives from L- rhamnose with expected biological activity
title_fullStr Synthesis of some nucleosides derivatives from L- rhamnose with expected biological activity
title_full_unstemmed Synthesis of some nucleosides derivatives from L- rhamnose with expected biological activity
title_short Synthesis of some nucleosides derivatives from L- rhamnose with expected biological activity
title_sort synthesis of some nucleosides derivatives from l- rhamnose with expected biological activity
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047426/
https://www.ncbi.nlm.nih.gov/pubmed/21314940
http://dx.doi.org/10.1186/1752-153X-5-7
work_keys_str_mv AT ghoneimamiraatef synthesisofsomenucleosidesderivativesfromlrhamnosewithexpectedbiologicalactivity

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