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Structure of HsdS Subunit from Thermoanaerobacter tengcongensis Sheds Lights on Mechanism of Dynamic Opening and Closing of Type I Methyltransferase

Type I DNA methyltransferases contain one specificity subunit (HsdS) and two modification subunits (HsdM). The electron microscopy model of M.EcoKI-M(2)S(1) methyltransferase shows a reasonable closed state of this clamp-like enzyme, but the structure of the open state is still unclear. The 1.95 Å c...

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Detalles Bibliográficos
Autores principales: Gao, Pu, Tang, Qun, An, XiaoMin, Yan, XiaoXue, Liang, DongCai
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047542/
https://www.ncbi.nlm.nih.gov/pubmed/21399684
http://dx.doi.org/10.1371/journal.pone.0017346

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