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Voltage- and temperature-dependent activation of TRPV3 channels is potentiated by receptor-mediated PI(4,5)P(2) hydrolysis

TRPV3 is a thermosensitive channel that is robustly expressed in skin keratinocytes and activated by innocuous thermal heating, membrane depolarization, and chemical agonists such as 2-aminoethyoxy diphenylborinate, carvacrol, and camphor. TRPV3 modulates sensory thermotransduction, hair growth, and...

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Detalles Bibliográficos
Autores principales: Doerner, Julia F., Hatt, Hanns, Ramsey, I. Scott
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047606/
https://www.ncbi.nlm.nih.gov/pubmed/21321070
http://dx.doi.org/10.1085/jgp.200910388

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