Cell Therapy for Cardiovascular Disease: A Comparison of Methods of Delivery

The field of myocardial regeneration utilizing novel cell-based therapies, gene transfer, and growth factors may prove to play an important role in the future management of ischemic heart disease and cardiomyopathy. Phases I and II clinical trials have been published for a variety of biologics utili...

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Detalles Bibliográficos
Autores principales: Dib, Nabil, Khawaja, Harris, Varner, Samantha, McCarthy, Megan, Campbell, Ann
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047684/
https://www.ncbi.nlm.nih.gov/pubmed/21181320
http://dx.doi.org/10.1007/s12265-010-9253-z
Descripción
Sumario:The field of myocardial regeneration utilizing novel cell-based therapies, gene transfer, and growth factors may prove to play an important role in the future management of ischemic heart disease and cardiomyopathy. Phases I and II clinical trials have been published for a variety of biologics utilizing four methods of delivery: systemic infusion, intracoronary infusion, transvenous coronary sinus, and intramyocardial. This review discusses the advantages and disadvantages of the delivery approaches above.

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