Cell Therapy for Cardiovascular Disease: A Comparison of Methods of Delivery

The field of myocardial regeneration utilizing novel cell-based therapies, gene transfer, and growth factors may prove to play an important role in the future management of ischemic heart disease and cardiomyopathy. Phases I and II clinical trials have been published for a variety of biologics utili...

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Detalles Bibliográficos
Autores principales: Dib, Nabil, Khawaja, Harris, Varner, Samantha, McCarthy, Megan, Campbell, Ann
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047684/
https://www.ncbi.nlm.nih.gov/pubmed/21181320
http://dx.doi.org/10.1007/s12265-010-9253-z
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author Dib, Nabil
Khawaja, Harris
Varner, Samantha
McCarthy, Megan
Campbell, Ann
author_facet Dib, Nabil
Khawaja, Harris
Varner, Samantha
McCarthy, Megan
Campbell, Ann
author_sort Dib, Nabil
collection PubMed
description The field of myocardial regeneration utilizing novel cell-based therapies, gene transfer, and growth factors may prove to play an important role in the future management of ischemic heart disease and cardiomyopathy. Phases I and II clinical trials have been published for a variety of biologics utilizing four methods of delivery: systemic infusion, intracoronary infusion, transvenous coronary sinus, and intramyocardial. This review discusses the advantages and disadvantages of the delivery approaches above.
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spelling pubmed-30476842011-04-05 Cell Therapy for Cardiovascular Disease: A Comparison of Methods of Delivery Dib, Nabil Khawaja, Harris Varner, Samantha McCarthy, Megan Campbell, Ann J Cardiovasc Transl Res Article The field of myocardial regeneration utilizing novel cell-based therapies, gene transfer, and growth factors may prove to play an important role in the future management of ischemic heart disease and cardiomyopathy. Phases I and II clinical trials have been published for a variety of biologics utilizing four methods of delivery: systemic infusion, intracoronary infusion, transvenous coronary sinus, and intramyocardial. This review discusses the advantages and disadvantages of the delivery approaches above. Springer US 2010-12-23 2011 /pmc/articles/PMC3047684/ /pubmed/21181320 http://dx.doi.org/10.1007/s12265-010-9253-z Text en © The Author(s) 2010 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Article
Dib, Nabil
Khawaja, Harris
Varner, Samantha
McCarthy, Megan
Campbell, Ann
Cell Therapy for Cardiovascular Disease: A Comparison of Methods of Delivery
title Cell Therapy for Cardiovascular Disease: A Comparison of Methods of Delivery
title_full Cell Therapy for Cardiovascular Disease: A Comparison of Methods of Delivery
title_fullStr Cell Therapy for Cardiovascular Disease: A Comparison of Methods of Delivery
title_full_unstemmed Cell Therapy for Cardiovascular Disease: A Comparison of Methods of Delivery
title_short Cell Therapy for Cardiovascular Disease: A Comparison of Methods of Delivery
title_sort cell therapy for cardiovascular disease: a comparison of methods of delivery
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047684/
https://www.ncbi.nlm.nih.gov/pubmed/21181320
http://dx.doi.org/10.1007/s12265-010-9253-z
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AT mccarthymegan celltherapyforcardiovasculardiseaseacomparisonofmethodsofdelivery
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