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Peripartum cardiomyopathy: the need for a national database

Peripartum cardiomyopathy (PPCM) is a rare and life-threatening disease that affects young women in the last month of pregnancy or within 5 months of delivery. It is a form of dilated cardiomyopathy with left-sided systolic dysfunction. The incidence rate in the Western world is estimated to be 1:30...

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Autores principales: Lok, S. I., Kirkels, J. H., Klöpping, C., Doevendans, P. A. F., de Jonge, N.
Formato: Texto
Lenguaje:English
Publicado: Bohn Stafleu van Loghum 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047689/
https://www.ncbi.nlm.nih.gov/pubmed/21475400
http://dx.doi.org/10.1007/s12471-011-0083-7
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author Lok, S. I.
Kirkels, J. H.
Klöpping, C.
Doevendans, P. A. F.
de Jonge, N.
author_facet Lok, S. I.
Kirkels, J. H.
Klöpping, C.
Doevendans, P. A. F.
de Jonge, N.
author_sort Lok, S. I.
collection PubMed
description Peripartum cardiomyopathy (PPCM) is a rare and life-threatening disease that affects young women in the last month of pregnancy or within 5 months of delivery. It is a form of dilated cardiomyopathy with left-sided systolic dysfunction. The incidence rate in the Western world is estimated to be 1:3000. Symptoms of PPCM vary greatly and may be obscured by common physiological aspects of pregnancy. Therefore, the incidence rate might be higher. Echocardiography or MRI can confirm or rule out PPCM. Unfortunately, there is no specific risk factor profile available. The clinical course varies from complete recovery to deterioration of cardiac function. Patients with PPCM, especially those whose ventricular function has not returned to normal, are advised against further pregnancy. Recently, more disease-specific therapeutic strategies have been developed with promising results for prolactin blockade by bromocriptine. Increasing awareness for PPCM among general practitioners, gynaecologists and cardiologists may help to diagnose patients efficiently in order to start adequate treatment. A national registry is warranted to identify risk factor profiles and to optimise treatment strategies.
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spelling pubmed-30476892011-04-05 Peripartum cardiomyopathy: the need for a national database Lok, S. I. Kirkels, J. H. Klöpping, C. Doevendans, P. A. F. de Jonge, N. Neth Heart J Review Article Peripartum cardiomyopathy (PPCM) is a rare and life-threatening disease that affects young women in the last month of pregnancy or within 5 months of delivery. It is a form of dilated cardiomyopathy with left-sided systolic dysfunction. The incidence rate in the Western world is estimated to be 1:3000. Symptoms of PPCM vary greatly and may be obscured by common physiological aspects of pregnancy. Therefore, the incidence rate might be higher. Echocardiography or MRI can confirm or rule out PPCM. Unfortunately, there is no specific risk factor profile available. The clinical course varies from complete recovery to deterioration of cardiac function. Patients with PPCM, especially those whose ventricular function has not returned to normal, are advised against further pregnancy. Recently, more disease-specific therapeutic strategies have been developed with promising results for prolactin blockade by bromocriptine. Increasing awareness for PPCM among general practitioners, gynaecologists and cardiologists may help to diagnose patients efficiently in order to start adequate treatment. A national registry is warranted to identify risk factor profiles and to optimise treatment strategies. Bohn Stafleu van Loghum 2011-01-27 2011-03 /pmc/articles/PMC3047689/ /pubmed/21475400 http://dx.doi.org/10.1007/s12471-011-0083-7 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Review Article
Lok, S. I.
Kirkels, J. H.
Klöpping, C.
Doevendans, P. A. F.
de Jonge, N.
Peripartum cardiomyopathy: the need for a national database
title Peripartum cardiomyopathy: the need for a national database
title_full Peripartum cardiomyopathy: the need for a national database
title_fullStr Peripartum cardiomyopathy: the need for a national database
title_full_unstemmed Peripartum cardiomyopathy: the need for a national database
title_short Peripartum cardiomyopathy: the need for a national database
title_sort peripartum cardiomyopathy: the need for a national database
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047689/
https://www.ncbi.nlm.nih.gov/pubmed/21475400
http://dx.doi.org/10.1007/s12471-011-0083-7
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