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Management of tinea capitis in childhood
Tinea capitis (TC) is a common dermatophyte infection affecting primarily prepubertal children. The causative pathogens belong to only two genera: Trichophyton and Microsporum. Although there is a great local variation in the epidemiology of TC worldwide, T. tonsurans is currently the most common ca...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Dove Medical Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047946/ https://www.ncbi.nlm.nih.gov/pubmed/21437064 |
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author | Bennassar, Antoni Grimalt, Ramon |
author_facet | Bennassar, Antoni Grimalt, Ramon |
author_sort | Bennassar, Antoni |
collection | PubMed |
description | Tinea capitis (TC) is a common dermatophyte infection affecting primarily prepubertal children. The causative pathogens belong to only two genera: Trichophyton and Microsporum. Although there is a great local variation in the epidemiology of TC worldwide, T. tonsurans is currently the most common cause of TC with M. canis second. Even though there is an emerging number of anthropophilic scalp infections, M. canis remains the predominant causative organism in many countries of the Mediterranean basin, the most important dermatophyte carriers being stray cats and dogs as well as pet puppies, kittens and rabbits. TC always requires systemic treatment because topical antifungal agents do not penetrate down to the deepest part of the hair follicle. Since the late 1950s, griseofulvin has been the gold standard for systemic therapy of TC. It is active against dermatophytes and has a long-term safety profile. The main disadvantage of griseofulvin is the long duration of treatment required which may lead to reduced compliance. The newer oral antifungal agents including terbinafine, itraconazole, ketokonazole, and fluconazole appear to have efficacy rates and potential adverse effects similar to those of griseofulvin in children with TC caused by Trichophyton species, while requiring a much shorter duration of treatment. They may, however, be more expensive. |
format | Text |
id | pubmed-3047946 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-30479462011-03-23 Management of tinea capitis in childhood Bennassar, Antoni Grimalt, Ramon Clin Cosmet Investig Dermatol Review Tinea capitis (TC) is a common dermatophyte infection affecting primarily prepubertal children. The causative pathogens belong to only two genera: Trichophyton and Microsporum. Although there is a great local variation in the epidemiology of TC worldwide, T. tonsurans is currently the most common cause of TC with M. canis second. Even though there is an emerging number of anthropophilic scalp infections, M. canis remains the predominant causative organism in many countries of the Mediterranean basin, the most important dermatophyte carriers being stray cats and dogs as well as pet puppies, kittens and rabbits. TC always requires systemic treatment because topical antifungal agents do not penetrate down to the deepest part of the hair follicle. Since the late 1950s, griseofulvin has been the gold standard for systemic therapy of TC. It is active against dermatophytes and has a long-term safety profile. The main disadvantage of griseofulvin is the long duration of treatment required which may lead to reduced compliance. The newer oral antifungal agents including terbinafine, itraconazole, ketokonazole, and fluconazole appear to have efficacy rates and potential adverse effects similar to those of griseofulvin in children with TC caused by Trichophyton species, while requiring a much shorter duration of treatment. They may, however, be more expensive. Dove Medical Press 2010-07-14 /pmc/articles/PMC3047946/ /pubmed/21437064 Text en © 2010 Bennassar and Grimalt, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Review Bennassar, Antoni Grimalt, Ramon Management of tinea capitis in childhood |
title | Management of tinea capitis in childhood |
title_full | Management of tinea capitis in childhood |
title_fullStr | Management of tinea capitis in childhood |
title_full_unstemmed | Management of tinea capitis in childhood |
title_short | Management of tinea capitis in childhood |
title_sort | management of tinea capitis in childhood |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047946/ https://www.ncbi.nlm.nih.gov/pubmed/21437064 |
work_keys_str_mv | AT bennassarantoni managementoftineacapitisinchildhood AT grimaltramon managementoftineacapitisinchildhood |