Cargando…

Differential HFE Gene Expression Is Regulated by Alternative Splicing in Human Tissues

BACKGROUND: The pathophysiology of HFE-derived Hereditary Hemochromatosis and the function of HFE protein in iron homeostasis remain uncertain. Also, the role of alternative splicing in HFE gene expression regulation and the possible function of the corresponding protein isoforms are still unknown....

Descripción completa

Detalles Bibliográficos
Autores principales: Martins, Rute, Silva, Bruno, Proença, Daniela, Faustino, Paula
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048171/
https://www.ncbi.nlm.nih.gov/pubmed/21407826
http://dx.doi.org/10.1371/journal.pone.0017542