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Sterilizing Activity of Second-Line Regimens Containing TMC207 in a Murine Model of Tuberculosis

RATIONALE: The sterilizing activity of the regimen used to treat multidrug resistant tuberculosis (MDR TB) has not been studied in a mouse model. OBJECTIVE AND METHODS: Swiss mice were intravenously inoculated with 6 log10 of Mycobacterium tuberculosis (TB) strain H37Rv, treated with second-line dru...

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Detalles Bibliográficos
Autores principales:	Veziris, Nicolas, Ibrahim, Murad, Lounis, Nacer, Andries, Koen, Jarlier, Vincent
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048299/ https://www.ncbi.nlm.nih.gov/pubmed/21408613 http://dx.doi.org/10.1371/journal.pone.0017556

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