Cargando…

Generation of Functional Neutrophils from a Mouse Model of X-Linked Chronic Granulomatous Disorder Using Induced Pluripotent Stem Cells

Murine models of human genetic disorders provide a valuable tool for investigating the scope for application of induced pluripotent stem cells (iPSC). Here we present a proof-of-concept study to demonstrate generation of iPSC from a mouse model of X-linked chronic granulomatous disease (X-CGD), and...

Descripción completa

Detalles Bibliográficos
Autores principales: Mukherjee, Sayandip, Santilli, Giorgia, Blundell, Michael P., Navarro, Susana, Bueren, Juan A., Thrasher, Adrian J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048300/
https://www.ncbi.nlm.nih.gov/pubmed/21408614
http://dx.doi.org/10.1371/journal.pone.0017565