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Generation of Functional Neutrophils from a Mouse Model of X-Linked Chronic Granulomatous Disorder Using Induced Pluripotent Stem Cells
Murine models of human genetic disorders provide a valuable tool for investigating the scope for application of induced pluripotent stem cells (iPSC). Here we present a proof-of-concept study to demonstrate generation of iPSC from a mouse model of X-linked chronic granulomatous disease (X-CGD), and...
Autores principales: | Mukherjee, Sayandip, Santilli, Giorgia, Blundell, Michael P., Navarro, Susana, Bueren, Juan A., Thrasher, Adrian J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048300/ https://www.ncbi.nlm.nih.gov/pubmed/21408614 http://dx.doi.org/10.1371/journal.pone.0017565 |
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