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Nucleotide Binding Switches the Information Flow in Ras GTPases

The Ras superfamily comprises many guanine nucleotide-binding proteins (G proteins) that are essential to intracellular signal transduction. The guanine nucleotide-dependent intrinsic flexibility patterns of five G proteins were investigated in atomic detail through Molecular Dynamics simulations of...

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Detalles Bibliográficos
Autores principales:	Raimondi, Francesco, Portella, Guillem, Orozco, Modesto, Fanelli, Francesca
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048383/ https://www.ncbi.nlm.nih.gov/pubmed/21390270 http://dx.doi.org/10.1371/journal.pcbi.1001098

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