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Identifying Causal Genes and Dysregulated Pathways in Complex Diseases
In complex diseases, various combinations of genomic perturbations often lead to the same phenotype. On a molecular level, combinations of genomic perturbations are assumed to dys-regulate the same cellular pathways. Such a pathway-centric perspective is fundamental to understanding the mechanisms o...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048384/ https://www.ncbi.nlm.nih.gov/pubmed/21390271 http://dx.doi.org/10.1371/journal.pcbi.1001095 |