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Murine Melanoma-Infiltrating Dendritic Cells Are Defective in Antigen Presenting Function Regardless of the Presence of CD4(+)CD25(+) Regulatory T Cells

Tumor-infiltrating dendritic cells are often ineffective at presenting tumor-derived antigen in vivo, a defect usually ascribed to the suppressive tumor environment. We investigated the effects of depleting CD4(+)CD25(+) “natural” regulatory T cells (Treg) on the frequency, phenotype and function of...

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Detalles Bibliográficos
Autores principales:	Ataera, Haley, Hyde, Evelyn, Price, Kylie M., Stoitzner, Patrizia, Ronchese, Franca
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048402/ https://www.ncbi.nlm.nih.gov/pubmed/21390236 http://dx.doi.org/10.1371/journal.pone.0017515

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