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Sensitivity of MRI Tumor Biomarkers to VEGFR Inhibitor Therapy in an Orthotopic Mouse Glioma Model
MRI biomarkers of tumor edema, vascular permeability, blood volume, and average vessel caliber are increasingly being employed to assess the efficacy of tumor therapies. However, the dependence of these biomarkers on a number of physiological factors can compromise their sensitivity and complicate t...
Autores principales: | Farrar, Christian T., Kamoun, Walid S., Ley, Carsten D., Kim, Young R., Catana, Ciprian, Kwon, Seon J., Rosen, Bruce R., Jain, Rakesh K., Sorensen, A. Gregory |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048404/ https://www.ncbi.nlm.nih.gov/pubmed/21390238 http://dx.doi.org/10.1371/journal.pone.0017228 |
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