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Two-step cleavage of hairpin RNA with 5' overhangs by human DICER

BACKGROUND: DICER is an RNase III family endoribonuclease that processes precursor microRNAs (pre-miRNAs) and long double-stranded RNAs, generating microRNA (miRNA) duplexes and short interfering RNA duplexes with 20~23 nucleotides (nts) in length. The typical form of pre-miRNA processed by the Dros...

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Detalles Bibliográficos
Autores principales:	Ando, Yoshinari, Maida, Yoshiko, Morinaga, Ayako, Burroughs, Alexander M, Kimura, Ryuichiro, Chiba, Joe, Suzuki, Harukazu, Masutomi, Kenkichi, Hayashizaki, Yoshihide
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048551/ https://www.ncbi.nlm.nih.gov/pubmed/21306637 http://dx.doi.org/10.1186/1471-2199-12-6

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