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Crystal structure of unliganded TRAP: implications for dynamic allostery
Allostery is vital to the function of many proteins. In some cases, rather than a direct steric effect, mutual modulation of ligand binding at spatially separated sites may be achieved through a change in protein dynamics. Thus changes in vibrational modes of the protein, rather than conformational...
Autores principales: | Malay, Ali D., Watanabe, Masahiro, Heddle, Jonathan G., Tame, Jeremy R. H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048579/ https://www.ncbi.nlm.nih.gov/pubmed/21175426 http://dx.doi.org/10.1042/BJ20101813 |
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