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Crystal structure of unliganded TRAP: implications for dynamic allostery

Allostery is vital to the function of many proteins. In some cases, rather than a direct steric effect, mutual modulation of ligand binding at spatially separated sites may be achieved through a change in protein dynamics. Thus changes in vibrational modes of the protein, rather than conformational...

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Detalles Bibliográficos
Autores principales: Malay, Ali D., Watanabe, Masahiro, Heddle, Jonathan G., Tame, Jeremy R. H.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048579/
https://www.ncbi.nlm.nih.gov/pubmed/21175426
http://dx.doi.org/10.1042/BJ20101813

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