Interleukin-6 Induces Gr-1+CD11b+ Myeloid Cells to Suppress CD8+ T Cell-Mediated Liver Injury in Mice

BACKGROUND: Agonist antibodies against CD137 (4–1BB) on T lymphocytes are used to increase host anti-tumor immunity, but often leading to severe liver injury in treated mice or in patients during clinical trials. Interleukin-6 (IL-6) has been reported to protect hepatocyte death, but the role of IL-...

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Detalles Bibliográficos
Autores principales: Cheng, Liang, Wang, Jun, Li, Xiaozhu, Xing, Qiao, Du, Peishuang, Su, Lishan, Wang, Shengdian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048877/
https://www.ncbi.nlm.nih.gov/pubmed/21394214
http://dx.doi.org/10.1371/journal.pone.0017631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048877/
https://www.ncbi.nlm.nih.gov/pubmed/21394214
http://dx.doi.org/10.1371/journal.pone.0017631

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