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β-TrCP is dispensable for Vpu's ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 release

BACKGROUND: The cellular transmembrane protein CD317/BST-2/HM1.24/Tetherin restricts HIV-1 infection by physically tethering mature virions to the surface of infected cells. HIV-1 counteracts this restriction by expressing the accessory protein Vpu, yet the mechanism of this antagonism is incomplete...

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Detalles Bibliográficos
Autores principales:	Tervo, Hanna-Mari, Homann, Stefanie, Ambiel, Ina, Fritz, Joëlle V, Fackler, Oliver T, Keppler, Oliver T
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049139/ https://www.ncbi.nlm.nih.gov/pubmed/21310048 http://dx.doi.org/10.1186/1742-4690-8-9

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