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Two-photon NADH imaging exposes boundaries of oxygen diffusion in cortical vascular supply regions
Oxygen transport imposes a possible constraint on the brain's ability to sustain variable metabolic demands, but oxygen diffusion in the cerebral cortex has not yet been observed directly. We show that concurrent two-photon fluorescence imaging of endogenous nicotinamide adenine dinucleotide (N...
Autores principales: | Kasischke, Karl A, Lambert, Elton M, Panepento, Ben, Sun, Anita, Gelbard, Harris A, Burgess, Robert W, Foster, Thomas H, Nedergaard, Maiken |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049466/ https://www.ncbi.nlm.nih.gov/pubmed/20859293 http://dx.doi.org/10.1038/jcbfm.2010.158 |
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