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Enhancement of osteoclastogenic activity in osteolytic prostate cancer cells by physical contact with osteoblasts

BACKGROUND: The interaction between prostate cancer cells and osteoblasts is critical for the development of bone metastasis. Metastatic cancer cells may physically contact osteoblasts in the bone microenvironment; however, the biological significance of this interaction is not fully understood. MET...

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Detalles Bibliográficos
Autores principales: Shiirevnyamba, A, Takahashi, T, Shan, H, Ogawa, H, Yano, S, Kanayama, H, Izumi, K, Uehara, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049567/
https://www.ncbi.nlm.nih.gov/pubmed/21206493
http://dx.doi.org/10.1038/sj.bjc.6606070