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ERK5 signalling in prostate cancer promotes an invasive phenotype

BACKGROUND: Aberrant mitogen/extracellular signal-regulated kinase 5 (MEK5)–extracellular signal-regulated protein kinase 5 (ERK5)-mediated signalling has been implicated in a number of tumour types including prostate cancer (PCa). The molecular basis of ERK5-driven carcinogenesis and its clinical r...

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Detalles Bibliográficos
Autores principales: Ramsay, A K, McCracken, S R C, Soofi, M, Fleming, J, Yu, A X, Ahmad, I, Morland, R, Machesky, L, Nixon, C, Edwards, D R, Nuttall, R K, Seywright, M, Marquez, R, Keller, E, Leung, H Y
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049582/
https://www.ncbi.nlm.nih.gov/pubmed/21266977
http://dx.doi.org/10.1038/sj.bjc.6606062