Cargando…

ERK5 signalling in prostate cancer promotes an invasive phenotype

BACKGROUND: Aberrant mitogen/extracellular signal-regulated kinase 5 (MEK5)–extracellular signal-regulated protein kinase 5 (ERK5)-mediated signalling has been implicated in a number of tumour types including prostate cancer (PCa). The molecular basis of ERK5-driven carcinogenesis and its clinical r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ramsay, A K, McCracken, S R C, Soofi, M, Fleming, J, Yu, A X, Ahmad, I, Morland, R, Machesky, L, Nixon, C, Edwards, D R, Nuttall, R K, Seywright, M, Marquez, R, Keller, E, Leung, H Y
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049582/ https://www.ncbi.nlm.nih.gov/pubmed/21266977 http://dx.doi.org/10.1038/sj.bjc.6606062

Ejemplares similares

Upregulation of MAPK pathway is associated with survival in castrate-resistant prostate cancer
por: Mukherjee, R, et al.
Publicado: (2011)

Mitogenic growth signalling, DNA replication licensing, and survival are linked in prostate cancer
por: Dudderidge, T J, et al.
Publicado: (2007)

Evaluation of the fibroblast growth factor system as a potential target for therapy in human prostate cancer
por: Gowardhan, B, et al.
Publicado: (2005)

Identification of degradome components associated with prostate cancer progression by expression analysis of human prostatic tissues
por: Riddick, A C P, et al.
Publicado: (2005)

Androgen receptor phosphorylation at serine 515 by Cdk1 predicts biochemical relapse in prostate cancer patients
por: Willder, J M, et al.
Publicado: (2013)

Mir143 expression inversely correlates with nuclear ERK5 immunoreactivity in clinical prostate cancer
por: Ahmad, I, et al.
Publicado: (2013)

NFκB signalling is upregulated in a subset of castrate-resistant prostate cancer patients and correlates with disease progression
por: McCall, P, et al.
Publicado: (2012)

Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells
por: Dixon, K M, et al.
Publicado: (2013)

Expression and prognostic significance of Src family members in renal clear cell carcinoma
por: Qayyum, T, et al.
Publicado: (2012)

Tumour-derived alkaline phosphatase regulates tumour growth, epithelial plasticity and disease-free survival in metastatic prostate cancer
por: Rao, S R, et al.
Publicado: (2017)

Upregulated FGFR1 expression is associated with the transition of hormone-naive to castrate-resistant prostate cancer
por: Armstrong, K, et al.
Publicado: (2011)

The interrelationships between Src, Cav-1 and RhoGD12 in transitional cell carcinoma of the bladder
por: Qayyum, T, et al.
Publicado: (2012)

Human ex vivo prostate tissue model system identifies ING3 as an oncoprotein
por: McClurg, Urszula L, et al.
Publicado: (2018)

Phosphorylation of the androgen receptor is associated with reduced survival in hormone-refractory prostate cancer patients
por: McCall, P, et al.
Publicado: (2008)

PEA3/ETV4-related transcription factors coupled with active ERK signalling are associated with poor prognosis in gastric adenocarcinoma
por: Keld, R, et al.
Publicado: (2011)

Chronic bacterial inflammation induces prostatic intraepithelial neoplasia in mouse prostate
por: Elkahwaji, J E, et al.
Publicado: (2009)

Impact of differential cyclin D1 expression and localisation in prostate cancer
por: Comstock, C E S, et al.
Publicado: (2007)

Is PTEN loss associated with clinical outcome measures in human prostate cancer?
por: McCall, P, et al.
Publicado: (2008)

TEAD1 and c-Cbl are novel prostate basal cell markers that correlate with poor clinical outcome in prostate cancer
por: Knight, J F, et al.
Publicado: (2008)

IL-22 produced by cancer-associated fibroblasts promotes gastric cancer cell invasion via STAT3 and ERK signaling
por: Fukui, H, et al.
Publicado: (2014)

Levels of a subpopulation of platelets, but not circulating endothelial cells, predict early treatment failure in prostate cancer patients after prostatectomy
por: Wong, C K E, et al.
Publicado: (2012)

Serum GADD45a methylation is a useful biomarker to distinguish benign vs malignant prostate disease
por: Reis, I M, et al.
Publicado: (2015)

Changes in circulating microRNA levels associated with prostate cancer
por: Bryant, R J, et al.
Publicado: (2012)

Expression levels of the JAK/STAT pathway in the transition from hormone-sensitive to hormone-refractory prostate cancer
por: Tam, L, et al.
Publicado: (2007)

Enhancement of the activity of phenoxodiol by cisplatin in prostate cancer cells
por: McPherson, R A C, et al.
Publicado: (2009)

GOLPH2 protein expression as a novel tissue biomarker for prostate cancer: implications for tissue-based diagnostics
por: Kristiansen, G, et al.
Publicado: (2008)

Construction of tissue microarrays from prostate needle biopsy specimens
por: Jhavar, S, et al.
Publicado: (2005)

Co-culturing human prostate carcinoma cells with hepatocytes leads to increased expression of E-cadherin
por: Yates, C C, et al.
Publicado: (2007)

DKC1 overexpression associated with prostate cancer progression
por: Sieron, P, et al.
Publicado: (2009)

Inactivation of the WASF3 gene in prostate cancer cells leads to suppression of tumorigenicity and metastases
por: Teng, Y, et al.
Publicado: (2010)

Prognostic relevance of Tiam1 protein expression in prostate carcinomas
por: Engers, R, et al.
Publicado: (2006)

Dissecting the expression of EEF1A1/2 genes in human prostate cancer cells: the potential of EEF1A2 as a hallmark for prostate transformation and progression
por: Scaggiante, B, et al.
Publicado: (2012)

Dexamethasone potentiates the antiangiogenic activity of docetaxel in castration-resistant prostate cancer
por: Wilson, C, et al.
Publicado: (2008)

Plasma osteopontin as a biomarker of prostate cancer aggression: relationship to risk category and treatment response
por: Thoms, J W, et al.
Publicado: (2012)

microRNA-183 is an oncogene targeting Dkk-3 and SMAD4 in prostate cancer
por: Ueno, K, et al.
Publicado: (2013)

Expression and prognostic relevance of activated extracellular-regulated kinases (ERK1/2) in breast cancer
por: Milde-Langosch, K, et al.
Publicado: (2005)

Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy
por: Weichert, W, et al.
Publicado: (2008)

Diagnosis of prostate cancer by detection of minichromosome maintenance 5 protein in urine sediments
por: Dudderidge, T J, et al.
Publicado: (2010)

An expression signature of the angiogenic response in gastrointestinal neuroendocrine tumours: correlation with tumour phenotype and survival outcomes
por: Pinato, D J, et al.
Publicado: (2014)

The cAMP phosphodiesterase-4D7 (PDE4D7) is downregulated in androgen-independent prostate cancer cells and mediates proliferation by compartmentalising cAMP at the plasma membrane of VCaP prostate cancer cells
por: Henderson, D J P, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_5bfneb7j126d1r3ff4jriogs87