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Human prostate cell lines from normal and tumourigenic epithelia differ in the pattern and control of choline lipid headgroups released into the medium on stimulation of protein kinase C

BACKGROUND: Expression of protein kinase C alpha (PKCα) is elevated in prostate cancer (PCa); thus, we have studied whether the development of tumourigenesis in prostate epithelial cell lines modifies the normal pattern of choline (Cho) metabolite release on PKC activation. METHODS: Normal and tumou...

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Detalles Bibliográficos
Autores principales: Rumsby, M, Schmitt, J, Sharrard, M, Rodrigues, G, Stower, M, Maitland, N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049586/
https://www.ncbi.nlm.nih.gov/pubmed/21266973
http://dx.doi.org/10.1038/sj.bjc.6606077