Experimental orthotopic penetrating keratoplasty--a rat penetrating keratoplasty model.

An orthotopic penetrating keratoplasty model was developed in the rat. An oversized (0.5 mm) graft was used and 8 interrupted sutures were applied. These sutures were not removed. Eleven grafts out of 13 were rejected by the 3rd week in the disparate group (Brown Norway rat to Lewis rat transplantat...

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Detalles Bibliográficos
Autores principales: Tchah, H., Youn, D. H., Holland, E. J.
Formato: Texto
Lenguaje:English
Publicado: Korean Academy of Medical Sciences 1991
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049680/
https://www.ncbi.nlm.nih.gov/pubmed/1888445
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author Tchah, H.
Youn, D. H.
Holland, E. J.
author_facet Tchah, H.
Youn, D. H.
Holland, E. J.
author_sort Tchah, H.
collection PubMed
description An orthotopic penetrating keratoplasty model was developed in the rat. An oversized (0.5 mm) graft was used and 8 interrupted sutures were applied. These sutures were not removed. Eleven grafts out of 13 were rejected by the 3rd week in the disparate group (Brown Norway rat to Lewis rat transplantation group), which was characterized by edema, opacity, and neovascularization. All grafts remained clear in the syngeneic group (Lewis rat to Lewis rat transplantation group). Immunohistochemical examination was performed. This model seems to be a reliable and reproducible one to evaluate rejection reaction in corneal transplantation.
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spelling pubmed-30496802011-03-09 Experimental orthotopic penetrating keratoplasty--a rat penetrating keratoplasty model. Tchah, H. Youn, D. H. Holland, E. J. J Korean Med Sci Research Article An orthotopic penetrating keratoplasty model was developed in the rat. An oversized (0.5 mm) graft was used and 8 interrupted sutures were applied. These sutures were not removed. Eleven grafts out of 13 were rejected by the 3rd week in the disparate group (Brown Norway rat to Lewis rat transplantation group), which was characterized by edema, opacity, and neovascularization. All grafts remained clear in the syngeneic group (Lewis rat to Lewis rat transplantation group). Immunohistochemical examination was performed. This model seems to be a reliable and reproducible one to evaluate rejection reaction in corneal transplantation. Korean Academy of Medical Sciences 1991-03 /pmc/articles/PMC3049680/ /pubmed/1888445 Text en
spellingShingle Research Article
Tchah, H.
Youn, D. H.
Holland, E. J.
Experimental orthotopic penetrating keratoplasty--a rat penetrating keratoplasty model.
title Experimental orthotopic penetrating keratoplasty--a rat penetrating keratoplasty model.
title_full Experimental orthotopic penetrating keratoplasty--a rat penetrating keratoplasty model.
title_fullStr Experimental orthotopic penetrating keratoplasty--a rat penetrating keratoplasty model.
title_full_unstemmed Experimental orthotopic penetrating keratoplasty--a rat penetrating keratoplasty model.
title_short Experimental orthotopic penetrating keratoplasty--a rat penetrating keratoplasty model.
title_sort experimental orthotopic penetrating keratoplasty--a rat penetrating keratoplasty model.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049680/
https://www.ncbi.nlm.nih.gov/pubmed/1888445
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AT youndh experimentalorthotopicpenetratingkeratoplastyaratpenetratingkeratoplastymodel
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