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Role of cholesterol 24S-hydroxylase gene polymorphism (rs754203) in primary open angle glaucoma

PURPOSE: The enzyme cholesterol 24S-hydroxylase (Cyp46A1) is responsible for the conversion of cholesterol to its more polar metabolite 24S-hydroxycholesterol, thereby enabling the intracerebral elimination of cholesterol. An intronic single nucleotide polymorphism in the gene CYP46A1 (IVS2 −150 T&g...

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Detalles Bibliográficos
Autores principales:	Mossböck, Georg, Weger, Martin, Faschinger, Christoph, Schmut, Otto, Renner, Wilfried, Wedrich, Andreas, Zimmermann, Christina, El-Shabrawi, Yosuf
Formato:	Texto
Lenguaje:	English
Publicado:	Molecular Vision 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049739/ https://www.ncbi.nlm.nih.gov/pubmed/21386929

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