Crystal Structure of a Charge Engineered Human Lysozyme Having Enhanced Bactericidal Activity

Human lysozyme is a key component of the innate immune system, and recombinant forms of the enzyme represent promising leads in the search for therapeutic agents able to treat drug-resistant infections. The wild type protein, however, fails to participate effectively in clearance of certain infectio...

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Detalles Bibliográficos
Autores principales: Gill, Avinash, Scanlon, Thomas C., Osipovitch, Daniel C., Madden, Dean R., Griswold, Karl E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049763/
https://www.ncbi.nlm.nih.gov/pubmed/21408218
http://dx.doi.org/10.1371/journal.pone.0016788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049763/
https://www.ncbi.nlm.nih.gov/pubmed/21408218
http://dx.doi.org/10.1371/journal.pone.0016788

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