A High Throughput Screen Identifies Chemical Modulators of the Laminin-Induced Clustering of Dystroglycan and Aquaporin-4 in Primary Astrocytes

BACKGROUND: Aquaporin-4 (AQP4) constitutes the principal water channel in the brain and is clusteredat the perivascular astrocyte endfeet. This specific distribution of AQP4 plays a major role in maintaining water homeostasis in the brain. A growing body of evidence points to a role ofthe dystroglyc...

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Detalles Bibliográficos
Autores principales: Noël, Geoffroy, Stevenson, Sarah, Moukhles, Hakima
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049781/
https://www.ncbi.nlm.nih.gov/pubmed/21408176
http://dx.doi.org/10.1371/journal.pone.0017559

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