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Performance Deficits of NK1 Receptor Knockout Mice in the 5-Choice Serial Reaction-Time Task: Effects of d-Amphetamine, Stress and Time of Day
BACKGROUND: The neurochemical status and hyperactivity of mice lacking functional substance P-preferring NK1 receptors (NK1R-/-) resemble abnormalities in Attention Deficit Hyperactivity Disorder (ADHD). Here we tested whether NK1R-/- mice express other core features of ADHD (impulsivity and inatten...
Autores principales: | Yan, Ting Carrie, Dudley, Julia A., Weir, Ruth K., Grabowska, Ewelina M., Peña-Oliver, Yolanda, Ripley, Tamzin L., Hunt, Stephen P., Stephens, David N., Stanford, S. Clare |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049786/ https://www.ncbi.nlm.nih.gov/pubmed/21408181 http://dx.doi.org/10.1371/journal.pone.0017586 |
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