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5-[(E)-2-Fluorobenzylidene]-8-(2-fluorophenyl)-2-hydroxy-10-methyl-3,10-diazahexacyclo[10.7.1.1(3,7).0(2,11).0(7,11).0(16,20)]henicosa-1(20),12,14,16,18-pentaen-6-one
In the title compound, C(33)H(26)F(2)N(2)O(2), the piperidone ring adopts a half-chair conformation and the pyrrolidine rings adopt half-chair and envelope conformations. The two benzene rings make dihedral angles of 29.58 (5) and 76.33 (5)° with the mean plane of the 1,2-dihydroacenaphthylene uni...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050149/ https://www.ncbi.nlm.nih.gov/pubmed/21522712 http://dx.doi.org/10.1107/S1600536810052815 |
Sumario: | In the title compound, C(33)H(26)F(2)N(2)O(2), the piperidone ring adopts a half-chair conformation and the pyrrolidine rings adopt half-chair and envelope conformations. The two benzene rings make dihedral angles of 29.58 (5) and 76.33 (5)° with the mean plane of the 1,2-dihydroacenaphthylene unit. An intramolecular O—H⋯N hydrogen bond helps to stabilize the molecular structure. In the crystal, intermolecular C—H⋯F hydrogen bonds link the molecules into [010] chains. Weak C—H⋯π interactions are also observed. |
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