Ethyl 2-amino-6-benzyl-4,5,6,7-tetra­hydro­thieno[2,3-c]pyridine-3-carboxyl­ate

In the title compound, C(17)H(20)N(2)O(2)S, the tetra­hydro­pyridine ring adopts an envelope conformation with the N atom at the flap position; the phenyl ring makes a dihedral angle of 81.06 (10)° with the thio­phene ring. The amino group links with the carbonyl O atom via intra­molecular N—H⋯O hyd...

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Detalles Bibliográficos
Autores principales: Meng, Shuang-Ming, Wang, Ke-Wei, Xie, Hai, Fan, Yue-Qin, Guo, Yong
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050265/
https://www.ncbi.nlm.nih.gov/pubmed/21522725
http://dx.doi.org/10.1107/S1600536810051986
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author Meng, Shuang-Ming
Wang, Ke-Wei
Xie, Hai
Fan, Yue-Qin
Guo, Yong
author_facet Meng, Shuang-Ming
Wang, Ke-Wei
Xie, Hai
Fan, Yue-Qin
Guo, Yong
author_sort Meng, Shuang-Ming
collection PubMed
description In the title compound, C(17)H(20)N(2)O(2)S, the tetra­hydro­pyridine ring adopts an envelope conformation with the N atom at the flap position; the phenyl ring makes a dihedral angle of 81.06 (10)° with the thio­phene ring. The amino group links with the carbonyl O atom via intra­molecular N—H⋯O hydrogen bonding, forming a six-membered ring. In the crystal, inter­molecular N—H⋯O hydrogen bonds link the mol­ecules into infinite chains running along the b axis.
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spelling pubmed-30502652011-04-26 Ethyl 2-amino-6-benzyl-4,5,6,7-tetra­hydro­thieno[2,3-c]pyridine-3-carboxyl­ate Meng, Shuang-Ming Wang, Ke-Wei Xie, Hai Fan, Yue-Qin Guo, Yong Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(17)H(20)N(2)O(2)S, the tetra­hydro­pyridine ring adopts an envelope conformation with the N atom at the flap position; the phenyl ring makes a dihedral angle of 81.06 (10)° with the thio­phene ring. The amino group links with the carbonyl O atom via intra­molecular N—H⋯O hydrogen bonding, forming a six-membered ring. In the crystal, inter­molecular N—H⋯O hydrogen bonds link the mol­ecules into infinite chains running along the b axis. International Union of Crystallography 2010-12-24 /pmc/articles/PMC3050265/ /pubmed/21522725 http://dx.doi.org/10.1107/S1600536810051986 Text en © Meng et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Meng, Shuang-Ming
Wang, Ke-Wei
Xie, Hai
Fan, Yue-Qin
Guo, Yong
Ethyl 2-amino-6-benzyl-4,5,6,7-tetra­hydro­thieno[2,3-c]pyridine-3-carboxyl­ate
title Ethyl 2-amino-6-benzyl-4,5,6,7-tetra­hydro­thieno[2,3-c]pyridine-3-carboxyl­ate
title_full Ethyl 2-amino-6-benzyl-4,5,6,7-tetra­hydro­thieno[2,3-c]pyridine-3-carboxyl­ate
title_fullStr Ethyl 2-amino-6-benzyl-4,5,6,7-tetra­hydro­thieno[2,3-c]pyridine-3-carboxyl­ate
title_full_unstemmed Ethyl 2-amino-6-benzyl-4,5,6,7-tetra­hydro­thieno[2,3-c]pyridine-3-carboxyl­ate
title_short Ethyl 2-amino-6-benzyl-4,5,6,7-tetra­hydro­thieno[2,3-c]pyridine-3-carboxyl­ate
title_sort ethyl 2-amino-6-benzyl-4,5,6,7-tetra­hydro­thieno[2,3-c]pyridine-3-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050265/
https://www.ncbi.nlm.nih.gov/pubmed/21522725
http://dx.doi.org/10.1107/S1600536810051986
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