2-Amino-4-(4-fluoro­phen­yl)-6-(naphthalen-1-yl)pyridine-3-carbonitrile

The title compound, C(22)H(14)FN(3), was prepared by a one-pot condensation using malononitrile, an aromatic aldehyde, a methyl ketone and ammonium acetate as reacta­nts under microwave irradiation. The pyridine ring is twisted with respect to the benzene ring and the naphthalene ring system, making...

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Detalles Bibliográficos
Autores principales: Wang, Jian-Qiang, Tang, Shi-Gui, Guo, Cheng
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050308/
https://www.ncbi.nlm.nih.gov/pubmed/21522766
http://dx.doi.org/10.1107/S1600536810050804
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author Wang, Jian-Qiang
Tang, Shi-Gui
Guo, Cheng
author_facet Wang, Jian-Qiang
Tang, Shi-Gui
Guo, Cheng
author_sort Wang, Jian-Qiang
collection PubMed
description The title compound, C(22)H(14)FN(3), was prepared by a one-pot condensation using malononitrile, an aromatic aldehyde, a methyl ketone and ammonium acetate as reacta­nts under microwave irradiation. The pyridine ring is twisted with respect to the benzene ring and the naphthalene ring system, making dihedral angles of 41.9 (1) and 45.2 (1)°, respectively. In the crystal, mol­ecules are connected via inter­molecular N—H⋯N and C—H⋯F hydrogen bonds, forming a three-dimensional network.
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spelling pubmed-30503082011-04-26 2-Amino-4-(4-fluoro­phen­yl)-6-(naphthalen-1-yl)pyridine-3-carbonitrile Wang, Jian-Qiang Tang, Shi-Gui Guo, Cheng Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(22)H(14)FN(3), was prepared by a one-pot condensation using malononitrile, an aromatic aldehyde, a methyl ketone and ammonium acetate as reacta­nts under microwave irradiation. The pyridine ring is twisted with respect to the benzene ring and the naphthalene ring system, making dihedral angles of 41.9 (1) and 45.2 (1)°, respectively. In the crystal, mol­ecules are connected via inter­molecular N—H⋯N and C—H⋯F hydrogen bonds, forming a three-dimensional network. International Union of Crystallography 2010-12-08 /pmc/articles/PMC3050308/ /pubmed/21522766 http://dx.doi.org/10.1107/S1600536810050804 Text en © Wang et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Wang, Jian-Qiang
Tang, Shi-Gui
Guo, Cheng
2-Amino-4-(4-fluoro­phen­yl)-6-(naphthalen-1-yl)pyridine-3-carbonitrile
title 2-Amino-4-(4-fluoro­phen­yl)-6-(naphthalen-1-yl)pyridine-3-carbonitrile
title_full 2-Amino-4-(4-fluoro­phen­yl)-6-(naphthalen-1-yl)pyridine-3-carbonitrile
title_fullStr 2-Amino-4-(4-fluoro­phen­yl)-6-(naphthalen-1-yl)pyridine-3-carbonitrile
title_full_unstemmed 2-Amino-4-(4-fluoro­phen­yl)-6-(naphthalen-1-yl)pyridine-3-carbonitrile
title_short 2-Amino-4-(4-fluoro­phen­yl)-6-(naphthalen-1-yl)pyridine-3-carbonitrile
title_sort 2-amino-4-(4-fluoro­phen­yl)-6-(naphthalen-1-yl)pyridine-3-carbonitrile
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050308/
https://www.ncbi.nlm.nih.gov/pubmed/21522766
http://dx.doi.org/10.1107/S1600536810050804
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AT tangshigui 2amino44fluorophenyl6naphthalen1ylpyridine3carbonitrile
AT guocheng 2amino44fluorophenyl6naphthalen1ylpyridine3carbonitrile

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