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2-[4-(2-Methoxyphenyl)piperazin-1-yl]-N-(pyridin-2-yl)acetamide
In the title compound, C(18)H(22)N(4)O(2), the piperizine ring adopts a chair conformation and the dihedral angle between the pyridine and benzene rings is 67.6 (9)°. The conformations of the attachment of the anisole and N-ethylpyridin-2-amine groups to the piperazine ring are (+)antiperiplanar....
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050313/ https://www.ncbi.nlm.nih.gov/pubmed/21522722 http://dx.doi.org/10.1107/S1600536810053067 |
Sumario: | In the title compound, C(18)H(22)N(4)O(2), the piperizine ring adopts a chair conformation and the dihedral angle between the pyridine and benzene rings is 67.6 (9)°. The conformations of the attachment of the anisole and N-ethylpyridin-2-amine groups to the piperazine ring are (+)antiperiplanar. Intramolecular C—H⋯O and N—H⋯N interactions occur. In the crystal, intermolecular C—H⋯N hydrogen bonds are present. There are two crystallographically independent but identical molecules per asymmetric unit. |
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