2-[4-(2-Meth­oxy­phen­yl)piperazin-1-yl]-N-(pyridin-2-yl)acetamide

In the title compound, C(18)H(22)N(4)O(2), the piperizine ring adopts a chair conformation and the dihedral angle between the pyridine and benzene rings is 67.6 (9)°. The conformations of the attachment of the anisole and N-ethyl­pyridin-2-amine groups to the piperazine ring are (+)anti­periplanar....

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Detalles Bibliográficos
Autores principales: Lu, Chunxiong, Jiang, Quanfu
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050313/
https://www.ncbi.nlm.nih.gov/pubmed/21522722
http://dx.doi.org/10.1107/S1600536810053067
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author Lu, Chunxiong
Jiang, Quanfu
author_facet Lu, Chunxiong
Jiang, Quanfu
author_sort Lu, Chunxiong
collection PubMed
description In the title compound, C(18)H(22)N(4)O(2), the piperizine ring adopts a chair conformation and the dihedral angle between the pyridine and benzene rings is 67.6 (9)°. The conformations of the attachment of the anisole and N-ethyl­pyridin-2-amine groups to the piperazine ring are (+)anti­periplanar. Intra­molecular C—H⋯O and N—H⋯N inter­actions occur. In the crystal, inter­molecular C—H⋯N hydrogen bonds are present. There are two crystallographically independent but identical mol­ecules per asymmetric unit.
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spelling pubmed-30503132011-04-26 2-[4-(2-Meth­oxy­phen­yl)piperazin-1-yl]-N-(pyridin-2-yl)acetamide Lu, Chunxiong Jiang, Quanfu Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(18)H(22)N(4)O(2), the piperizine ring adopts a chair conformation and the dihedral angle between the pyridine and benzene rings is 67.6 (9)°. The conformations of the attachment of the anisole and N-ethyl­pyridin-2-amine groups to the piperazine ring are (+)anti­periplanar. Intra­molecular C—H⋯O and N—H⋯N inter­actions occur. In the crystal, inter­molecular C—H⋯N hydrogen bonds are present. There are two crystallographically independent but identical mol­ecules per asymmetric unit. International Union of Crystallography 2010-12-24 /pmc/articles/PMC3050313/ /pubmed/21522722 http://dx.doi.org/10.1107/S1600536810053067 Text en © Lu and Jiang 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Lu, Chunxiong
Jiang, Quanfu
2-[4-(2-Meth­oxy­phen­yl)piperazin-1-yl]-N-(pyridin-2-yl)acetamide
title 2-[4-(2-Meth­oxy­phen­yl)piperazin-1-yl]-N-(pyridin-2-yl)acetamide
title_full 2-[4-(2-Meth­oxy­phen­yl)piperazin-1-yl]-N-(pyridin-2-yl)acetamide
title_fullStr 2-[4-(2-Meth­oxy­phen­yl)piperazin-1-yl]-N-(pyridin-2-yl)acetamide
title_full_unstemmed 2-[4-(2-Meth­oxy­phen­yl)piperazin-1-yl]-N-(pyridin-2-yl)acetamide
title_short 2-[4-(2-Meth­oxy­phen­yl)piperazin-1-yl]-N-(pyridin-2-yl)acetamide
title_sort 2-[4-(2-meth­oxy­phen­yl)piperazin-1-yl]-n-(pyridin-2-yl)acetamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050313/
https://www.ncbi.nlm.nih.gov/pubmed/21522722
http://dx.doi.org/10.1107/S1600536810053067
work_keys_str_mv AT luchunxiong 242methoxyphenylpiperazin1ylnpyridin2ylacetamide
AT jiangquanfu 242methoxyphenylpiperazin1ylnpyridin2ylacetamide

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